Knox maintains splendid musical instruments that include a renovated and expanded 50-rank Holtkamp pipe organ,  a concert grand Steinway piano, a Flemish harpsichord, a five-octave set of Schulmerich handbells, and continuo organ by Juget-Sinclair of Montreal, Canada.

Knox Choir premiered its thirteenth anthem or hymn commission in January 2020. Here is a list of Knox Anthem and Hymn Commissions 1995-2020.

Listen to a recent Knox commission, Dominick DiOrio's Psalm 105, which premiered at Knox Church on September 24, 2017:

Over the last 40+ seasons the Knox Choir has produced an impressive number of major works for chorus and orchestra in worship and on the public Knox Music Series.  For examples from the Knox repertoire, click Knox Music Program- Major works list updated December 2019.